%0 Journal Article
%T Pyrrolizidine alkaloids from Bulgarian species of the genus Senecio
%A NADEZHDA KOSTOVA
%A VESELIN CHRISTOV
%A MAIA CHOLAKOVA
%A ELENA NIKOLOVA
%J Journal of the Serbian Chemical Society
%D 2006
%I Serbian Chemical Society
%X Nine Bulgarian species from the genus Senecio were studied phytochemically and/or by GC-MS analysis. Senecivernine-N-oxide was isolated and identified by spectral data for the first time. Different types of pyrrolizidine alkaloids were tested for cytotoxicity on murine lymphocytes. At a concentration of 100 ¦Ìg/ml, the alkaloid retroisosenine showed immunosuppressive effect.
%K Senecio
%K senecivernine-N-oxide
%K cytotoxicity
%K lymphocyte
%U http://www.shd.org.yu/HtDocs/SHD/Vol71/No12/JSCS_V71_No12-04.pdf