%0 Journal Article
%T A novel and efficient approach for the synthesis of new halo substituted 2-arylpyrazolo[4,3-c] coumarin derivatives
%A Pradeep Lokhande
%A Kamal Hasanzadeh
%A Shankaraiah Guruvaiah Konda
%J European Journal of Chemistry
%D 2011
%I 
%R 10.5155/eurjchem.2.2.223-228.336
%X A convenient protocol for the efficient synthesis of 2-arylpyrazolo[4,3-c]coumarins is described. The synthesis route involves molecular iodine catalyzed oxidative cyclization of 1-phenyl-3-(2'-hydroxyaryl)-4-formyl pyrazoles in dimethylsulfoxide. During the lactonisation of 4-formylpyrazoles, we found that iodine was incorporated into the unsubstituted O/P position of the 3-(2'-hydroxyaryl) group. Under similar conditions o-allyloxy derivative of pyrazoles gave same corresponding lactone derivatives by deallylation, lactonisation, and iodination in one step.
%K Iodine
%K Lactonisation
%K Deallylation
%K 2-Arylpyrazolo[4
%K 3-c]coumarins
%K Oxidation
%K Iodination
%U http://www.eurjchem.com/index.php/eurjchem/article/view/336