%0 Journal Article
%T Synthesis, characterization and antibacterial activity of nickel (II) and copper (II) complexes of N-(alkyl(aryl)carbamothioyl)-4-nitrobenzamide
%A Sohail Saeed
%A Naghmana Rashid
%A Muhammad Ali
%A Rizwan Hussain
%J European Journal of Chemistry
%D 2010
%I 
%R 10.5155/eurjchem.1.3.200-205.120
%X Nickel and copper metal complexes of N-(R-carbamothioyl)-4-nitrobenzamide (R = diphenyl and ethylbutyl) were synthesized and characterized by IR, 1H NMR, mass spectrometry and elemental analysis. The spectroscopic data are consistent with the ligand and the metal complexes containing two O and S chelated ligands. N-(diphenylcarbamothioyl)-4-nitrobenzamide, HL1, was characterized by a single crystal X-ray diffraction study. It crystallizes in the triclinic space group P  with unit cell dimensions of a = 6.8044(4)  , b = 10.0113(6)  , c = 13.2365(8)  , ¦Á = 6.8044(4) ¡ã, ¦Â = 78.171(4) ¡ã, ¦Ã = 13.2365(8)¡ã, V = 882.43(9)  3. The ligands coordinate as bidentates yielding essentially neutral complexes of the type [ML2]. The ligands and complexes were screened for their in vitro antibacterial activities and comparatively the complexes showed greater antibacterial efficacy than the thiourea derivative ligands.
%K Thiourea derivatives
%K Transition metal complexes
%K X-ray structure determination
%K Phase-transfer catalyst
%K Antibacterial activity
%U http://www.eurjchem.com/index.php/eurjchem/article/view/120