%0 Journal Article
%T Synthesis of octahydroquinazolinone derivatives using silica sulfuric acid as an efficient catalyst
%A Akbar Mobinikhaledi
%A Naser Foroughifar
%A Homila Khodaei
%J European Journal of Chemistry
%D 2010
%I 
%R 10.5155/eurjchem.1.4.291-293.108
%X Octahydroquinazolinone derivatives were synthesized in moderate to high yields via one-pot three component Biginelli reaction of dimedone, urea or thiourea and corresponding aromatic aldehydes in the presence of silica sulfuric acid as an efficient catalyst, in ethanol under reflux conditions. This protocol offers several advantages including good yields of products and easy experimental work-up procedure.
%K Quinazolinone
%K Silica sulfuric acid
%K Dimedone
%K Biginelli reaction
%U http://www.eurjchem.com/index.php/eurjchem/article/view/108