%0 Journal Article %T Synthesis and antimicrobial activity of some new 1,3-thiazoles, 1,3,4-thiadiazoles, 1,2,4-triazoles and 1,3-thiazines incorporating acridine and 1,2,3,4-tetrahydroacridine moieties %A Tarik El-Sayed Ali %A Azza Mohammed El-Kazak %J European Journal of Chemistry %D 2010 %I %R 10.5155/eurjchem.1.1.6-11.12 %X Some new sulfur-nitrogen heterocyclic systems such as 1,3-thiazoles, 1,3,4-thiadiazoles, 1,2,4-triazoles and 1,3-thiazines incorporating acridine and 1,2,3,4-tetrahydroacridine moieties were synthesized via heterocyclization of the key intermediate 4-(acridin-9-yl)-1-(1,2,3,4-tetrahydroacridin-9-ylcarbonyl)thiosemicarbazide. Structures of the new comp-ounds were established by elemental analyses and spectral data. All the products were also screened in vitro for their antimicrobial activity. %K Acridine %K 1 %K 2 %K 3 %K 4-Tetrahydroacridine %K S %K N-heterocycles %K Antimicrobial Activity %U http://www.eurjchem.com/index.php/eurjchem/article/view/12