%0 Journal Article
%T Dipeptide metabolites from the marine derived bacterium Streptomyces acrymicini
%A Hern¨˘ndez Isara L. C.
%A Macedo Mario L.
%A Berlinck Roberto G. S.
%A Ferreira Antonio G.
%J Journal of the Brazilian Chemical Society
%D 2004
%I Sociedade Brasileira de Qu¨Şmica, SBQ
%X The chemical investigation of the crude extract obtained from the growth media of the marine-derived actinomycete Streptomyces acrimycini isolated from marine sediments led to the isolation of two new dipeptide derivatives: 8-amino-[ 1,4] diazonane-2,5-dione (1) and leucyl-4-hydroxyproline (3). The dipeptides were isolated from the growth media by a series of chromatographic steps, and identified by analysis of spectroscopic data. The macrocyclic carbon backbone of 8-amino-[ 1,4] diazonane-2,5-dione has been previously reported only once in marinobactins, siderophores isolated from the marine bacterium Marinobacter sp.
%K 8-amino-[ 1
%K 4] diazonane-2
%K 5-dione
%K leucyl-4-hydroxyproline
%K Streptomyces acrimycini
%U http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532004000300017