%0 Journal Article
%T CARBON-BASED SOLID ACID CATALYZED SYNTHESIS OF POLYHYDROQUINOLINE DERIVATIVES VIA HANTZSCH REACTION UNDER SOLVENT-FREE CONDITIONS
%A ABOLGHASEM DAVOODNIA
%A AMIR KHOJASTEHNEZHAD
%J Journal of the Chilean Chemical Society
%D 2012
%I Sociedad Chilena de Qu¨Şmica
%X An easy method for the synthesis of polyhydroquinoline derivatives via one-pot four-component Hantzsch condensation of dimedone, aryl aldehydes, ethyl acetoacetate and ammonium acetate in the presence of a catalytic amount of carbon-based solid acid (CBSA) in solvent-free conditions is described. The main advantages of the present approach are relatively short reaction times, high product yields, clean reaction profiles, simple experimental and work-up procedure.
%K polyhydroquinoline derivatives
%K carbon-based solid acid
%K heterogeneous catalysis
%K solvent-free conditions
%U http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-97072012000400011