%0 Journal Article
%T Fatal Plasmodium falciparum, Clostridium perfringens, and Candida spp. Coinfections in a Traveler to Haiti
%A Gillian L. Genrich
%A Julu Bhatnagar
%A Christopher D. Paddock
%A Sherif R. Zaki
%J Journal of Tropical Medicine
%D 2009
%I Hindawi Publishing Corporation
%R 10.1155/2009/969070
%X Malaria is one of the most common causes of febrile illness in travelers. Coinfections with bacterial, viral, and fungal pathogens may not be suspected unless a patient fails to respond to malaria treatment. Using novel immunohistochemical and molecular techniques, Plasmodium falciparum, Clostridium perfringens, and Candida spp. coinfections were confirmed in a German traveler to Haiti. Plasmodium falciparum-induced ischemia may have increased this patient's susceptibility to C. perfringens and disseminated candidiasis leading to his death. When a patient presents with P. falciparum and shock and is unresponsive to malaria treatment, secondary infections should be suspected to initiate appropriate treatment.
%U http://www.hindawi.com/journals/jtm/2009/969070/