%0 Journal Article
%T Substituted Quinolinones. Part 16. Preparation and reactions of 3-(4-hydroxy-1-methyl-2-oxo-1,2-dihydroquinolin-3-yl)-3-oxopropanoic acid
%A Mohamed Abass
%A Elhossain Ali Mohamed
%A Mostafa Mohamed Ismail
%A Aisha Saleh Mayas
%J European Journal of Chemistry
%D 2011
%I 
%R 10.5155/eurjchem.2.3.378-387.351
%X Preparation of quinolinyl-3-oxopropanoic acid was accomplished by hydrolysis of pyranoquinolinedione, in aqueous alkaline medium. The chemical behavior of this ¦Â-keto acid towards nitrosation, coupling with a diazonium salt, esterification, condensation with 2,2-diethoxyethanamine, hydrazinolysis, Knoevenagel condensation with isatine, salicylaldehyde, 3-formylquinolones, and 3-formylchromone, was investigated. Also many of the products of these reactions were obtained using either pyranoquinolinedione 1 or ¦Â-keto acid 2, under the same conditions.
%K Quinolin-2(1H)-one
%K b-Keto-carboxylic acid
%K Pyrano[3
%K 2-c]quinoline
%K Knoevenagel condensation
%K Heterocyclization reactions
%K Organic synthesis
%U http://www.eurjchem.com/index.php/eurjchem/article/view/351