%0 Journal Article
%T Cross-linked polyethylene and bisphosphonate therapy for osteolysis in total hip arthroplasty: A case report.
%A O'Hara LJ
%A Nivbrant B
%A R£¿hrl S
%J Journal of Orthopaedic Surgery
%D 2004
%I Hong Kong Academy of Medicine Press
%X A 39-year-old woman underwent bilateral total hip arthroplasty with conventional, ethylene oxide-sterilised liners when she was a subject in a radiostereometric analysis study. Within 2 years she had rapid polyethylene wear with aggressive, asymptomatic, and periprosthetic osteolysis on both sides. Oral alendronate therapy halted the progression of osteolysis over a year and revision to cross-linked polyethylene liners was then undertaken while one stem was curettaged and the other revised. Radiostereometric analysis revealed a 96% reduction in wear rate over 2 years with the cross-linked liners. On stopping alendronate treatment, aggressive osteolysis recurred on the curretaged but not on the revised femur.
%U http://www.josonline.org/abstracts/v12n1/114.html