%0 Journal Article
%T Relationship between seasonal cold acclimatization and mtDNA haplogroup in Japanese
%A Nishimura Takayuki
%A Motoi Midori
%A Niri Yousuke
%A Hoshi Yoshikazu
%J Journal of Physiological Anthropology
%D 2012
%I BioMed Central
%R 10.1186/1880-6805-31-22
%X Background The purpose of this study was to elucidate the interaction between mtDNA haplogroup and seasonal variation that contributes to cold adaptation. Methods There were 15 subjects (seven haplotype D subjects and eight haplotype non-D subjects). In summer and winter, the subjects were placed in an environment where the ambient temperature dropped from 27 ˇăC to 10 ˇăC in 30 minutes. After that, they were exposed to cold for 60 minutes. Results In summer, the decrease in rectal temperature and increase in oxygen consumption was smaller and cold tolerance was higher in the haplotype non-D group than in the haplotype D group. In winter, no significant differences were seen in rectal temperature or oxygen consumption, but the respiratory exchange ratio decreased in the haplotype D group. Conclusions The results of the present study suggest that haplogroup D subjects are a group that changes energy metabolism more, and there appears to be a relationship between differences in cold adaptability and mtDNA polymorphism within the population. Moreover, group differences in cold adaptability seen in summer may decrease in winter due to supplementation by seasonal cold acclimatization.
%K Cold adaptation
%K Seasonal cold acclimatization
%K mtDNA haplogroup
%K Cold exposure
%K Oxygen consumption
%U http://www.jphysiolanthropol.com/content/31/1/22