%0 Journal Article
%T In-Vitro Cytotoxic and Thrombolytic Potential of Pothos Scandens L
%A Mohammad Mamun Ur Rashid
%A A.T.M Yusuf
%A Mohammed Mainul Hassan
%A Mohammed Aktar Sayeed
%J Journal of Pharmacognosy and Phytochemistry
%D 2013
%I AkiNik Publications
%X The methanolic extract of leaf of Pothos scandens was subjected to screening for cytotoxic activity by in-vitro brine shrimp lethality bioassay and thrombolytic activity. In brine shrimp bioassay, the crude methanolic extract of leaf showed strong cytotoxic activity with LC50 value of 14.195¦Ìg/ml compared to that of 0.305¦Ìg/ml exhibited by standard vincristine sulphate. During assay for thrombolytic activity, the methanolic extract of P. scandens revealed 19.451¡À1.711% lysis of clot while standard streptokinase (SK) and water, used as positive and negative controls, demonstrated 69.480¡À 2.651% and 3.0695¡À 0.497% lysis of clot, respectively.
%K Pothos scandens
%K Brine Shrimp Lethality
%K Thrombolytic
%K % lysis of clot
%K Vincristine
%K Streptokinase.
%U http://www.phytojournal.com/vol2Issue1/Issue_may_2013/51.pdf