%0 Journal Article
%T 高通量DNA合成测序化学研究进展<br/>Advance in Sequence Chemistry of High-Throughput DNA Sequencing by Synthesis
%A 陈婧
%A 肖鹏峰
%J Bioprocess
%P 1-6
%@ 2164-5582
%D 2012
%I Hans Publishing
%R 10.12677/bp.2012.21001
%X 高通量DNA测序是近年来发展起来的革命性技术，大大推动了快速、廉价获取基因组信息的能力，进而对生命科学产生深刻的影响。测序化学是高通量DNA测序的重要内容，且发展十分迅速；一些构思巧妙的新颖测序化学方法被相继报道，本文综述了高通量DNA测序化学的最新研究进展。<br />
High-throughput DNA sequencing, a revolutionized technology, greatly accelerated mining data from ge- nomes rapidly and cost-efficiently, thus have a profound impact on life sciences. Sequencing chemistry is a pivotal part of high-throughput DNA sequencing, and has been developed dramatically in recently years; a number of ingenious methods of novel sequencing chemistry by synthesis have been reported. In this paper, the development of high- throughput DNA sequencing chemistry by synthesis is reviewed.
%K 生物化学；高通量DNA测序；合成测序；测序化学<br/>Biochemistry
%K High-Throughput DNA Sequencing
%K DNA Sequencing-by-Synthesis
%K Sequencing Chemistry
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=544