%0 Journal Article
%T Genetic Aspects of Premature Ovarian Failure
%A Wieacker P
%J Journal f¨¹r Reproduktionsmedizin und Endokrinologie
%D 2009
%I Krause & Pachernegg GmbH
%X Premature ovarian failure (POF) is characterized by the combination of amenorrhea before age 40 years and hypergonadotropic hypogonadism. The prevalence is approximately 1 %. Genetic causes of POF include chromosome aberrations and monogenic defects. Furthermore, polygenic-multifactorial inheritance can be assumed in a subset of cases.
%K Chromosomenaberration
%K Genmutation
%K Humangenetik
%K POF
%K chromosome aberration
%K gene mutation
%K premature ovarian failure
%U http://www.kup.at/kup/pdf/7721.pdf