%0 Journal Article %T The effects of acute L-carnitine administration on ventilatory breakpoint and exercise performanceduring incremental exercise %A Mojtaba Kaviani %A Maryam Nourshahi %A Farhad Shokoohi %J Journal of Mazandaran University of Medical Sciences %D 2009 %I Mazandaran University of Medical Sciences %X (Received 31 October, 2009 ; Accepted 10 March, 2010)AbstractBackground and purpose: Many athletes adopt nutritional manipulations to improve their performance. Among the substances generally consumed is carnitine (L-trimethyl-3-hydroxy-ammoniobutanoate) which has been used by athletes as an ergogenic aid, due to its role in the transport of long-chain fatty acids across mitochondrial membranes. Nutritional supplements containing carbohydrates, proteins, vitamins, and minerals have been widely used in various sporting fields to provide a boost to the recommended daily allowance. The aim of this study is to investigate the effects of acute L-carnitine administration on ventilatory breakpoint, an exercise performance during incremental exercise.Materials and methods: This study was double-blind, randomized and crossover in design. The subjects were 12 randomly selected active male physical education students, 21.75¡À0.64 years old, with a mean body mass index (BMI) of 23.7¡À0.94kg/m2, divided into 2 groups. They received orally either 2g of L-carnitine dissolved in 200 ml of water, plus 6 drops of lemon juice or a placebo (6 ml lemon juice dissolved in 200 ml of water) 90 minutes before they began to exercise on a treadmill. They performed a modified protocol of Conconi test to exhaustion. One-way analysis of variance with repeated measurements was used for data analysis.Results: The results showed that exercise performance improved in LC group (2980¡À155 meter) compared with placebo group (2331¡À51 meter). Furthermore, no significant difference was found in ventilatory breakpoint between the two groups.Conclusion: This finding indicates that administration of L- Carnitine, 90 minutes prior to exercise may improve performance; despite the ventilatory breakpoint as one of the anaerobic system indices that had no effect. J Mazand Univ Med Sci 2009; 19(73): 43-50 (Persian). %K Exercise %K carnitine %K anaerobic threshod %U http://www.mazums.ac.ir/index.php?digital_library&do=downloadPdf&sid=829