%0 Journal Article
%T A case report and review of the literature: Ciprofloxacin resistant Salmonella enterica serovar Typhi in India
%A Belgode Narasimha Harish1
%A Godfred Antony Menezes1
%A Kengamuthu Sarangapani2
%A Subhash Chandra Parija1
%J Journal of Infection in Developing Countries
%D 2008
%I Open Learning on Enteric Pathogens
%X Background: Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones.Methods: The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution.Results: An isolate of Salmonella enterica serovar Typhi (S. Typhi) from a case of enteric fever gave a ciprofloxacin MIC of 64¦Ìg/ml.Conclusions: To our knowledge there have been no reports of such high-level resistance to ciprofloxacin in S. Typhi from southern India. HIMEDIA HiComb MIC test method is an alternative to the E-test. Ciprofloxacin resistant typhoid fever responds to treatment with ceftriaxzone.
%K Enteric fever
%K Salmonella Typhi
%K drug resistance
%U http://www.jidc.org/issn1972-2680/current-issue/68-vol-2-no-4-august-2008/168-a-case-report-and-review-of-the-literature-ciprofloxacin-resistant-salmonella-enterica-serovar-typhi-in-india