%0 Journal Article %T Metastatic Lymph Node Impostor in Pancreatic Cystadenocarcinoma %A Vu CKF %A Chang F %A Doig L %A Meenan J %J JOP Journal of the Pancreas %D 2005 %I E S Burioni Ricerche Bibliografiche %X CONTEXT: Lymph node involvement in pancreatic cancer is a predictor of poor patient long-term survival. The detection of multiple metastatic peri-pancreatic nodes by EUS-FNA may dissuade the surgeon from undertaking a curative pancreatic resection. CASE REPORT: We report an interesting case of a man with chronic lymphocytic leukemia, who presented with the diagnostic problem of a pancreatic solid-cystic lesion and multiple malignant-looking peri-pancreatic lymphadenopathy on EUS. EUS-FNA yielded chronic lymphocytic leukaemia involvement in the peri-pancreatic lymph nodes and a markedly elevated CEA in the cystic fluid. The absence of adenocarcinoma involvement of the lymph nodes prompted surgery on the pancreatic lesion with a curative intent. Pancreatic mucinous cystadenocarcinoma was diagnosed and a sub-total pancreatectomy was performed with clear resection margins. All 30 resected peri-pancreatic lymph nodes showed chronic lymphocytic leukemia involvement only. CONCLUSIONS: This case illustrates that abnormal lymphadenopathy adjacent to a primary pancreatic lesion may not necessarily be due to the latter. Systemic lymphoproliferative disease, as in this case, can masquerade as metastatic adenocarcinoma lymph nodes on EUS. EUS-FNA is useful in diagnosing lymphoproliferative disease. %K Aged %K Biopsy %K Fine-Needle %K Cystadenocarcinoma %K Cystadenocarcinoma %K Mucinous %K Cystadenocarcinoma /complications/diagnosis/secondary/surgery %K Diagnosis %K Differential %K Endosonography %K Humans %K Leukemia %K Lymphatic Diseases %K Leukemia %K Lymphocytic %K Chronic /complications/diagnosis/ultrasonography %K Lymph Nodes /pathology/surgery/ultrasonography %K Lymphatic Metastasis /diagnosis/pathology/ultrasonography %K Lymphocytic %K Chronic %K Male %K Pancreas /pathology/surgery/ultrasonography %K Pancreatectomy %K P %U http://www.joplink.net/prev/200503/04.html