%0 Journal Article
%T Palmoplantar Psoriasis: Treatment with Calcipotriol and Local UVA Radiation Compared with Local PUVA
%A Nikolai Tsankov
%A Simin Meymandi
%A Ivan Grozdev
%A Hamidreza Shafiei
%J Journal of Lasers in Medical Sciences
%D 2011
%I Shahid Beheshti University of Medical Sciences
%X INTRODUCTION: Palmoplantar psoriasis could hardly be differentiated from chronic tylotic eczema both clinically and histologically. The most commonly used therapeutic options for palmoplantar psoriasis are long-term therapy with topical corticosteroids and local PUVA. Frequently, it is a recalcitrant disease. We investigated the efficacy  and tolerability of the combination of topical calcipotriol with local UVA radiation in comparison with local PUVA therapy. METHODS: In a total of 43 patients with palmoplantar psoriasis, 33 were given 15 sessions of local UVA radiation and topical calcipotriol and the remainder received 15 sessions of local PUVA (psoralen + UVA radiation). RESULTS: The statistical analyses of the results showed that the effect and tolerability of both therapeutic modalities are comparable. CONCLUSION: Combination of topical calcipotriol and local UVA radiation is an optional corticosteroid-free therapeutic modality for palmoplantar psoriasis. It has a comparable effectiveness and tolerability with local PUVA.
%K Psoriasis
%K palmo-plantar
%K Calcipotriol
%K Psoralen
%K Clinical Trial
%U http://www.journals.sbmu.ac.ir/jlms/article/view/2110