%0 Journal Article
%T HEALING POTENTIAL OF GEL CONTAINING EXTRACT OF OUGEINIA OOJEINENSIS ON EXCISION WOUNDS IN WISTAR RATS
%A Ram Kumar Sahu
%A Vivek Kulshrestha
%A Sourabh Kothiya
%A Pavan Yadav
%J Journal of Global Pharma Technology
%D 2010
%I 
%R 10.1234/jgpt.v2i1.92
%X : To investigate the wound healing potency of ethanol and aqueous bark extracts of O. oojeinensis. Excision wound model was used to evaluate the wound healing activity of both the extracts on wistar rats. The rats were divided into four groups and each group has six rats. The group I was untreated and considered as control group. The group II was treated with neomycin cream and treated as standard group. The group III and group IV were treated with ethanol and aqueous extracts respectively. The extract was applied in the form gel (200 mg of extract incorporated with 100 gm of Carbopol 940 to get 0.2% w/w gel ) daily once times, starting from the excisions of skin from rats, till complete epithelialization. The healing of the wound was assessed by the rate of wound contraction and period of epithelialization. Both the ethanol and aqueous bark extracts promoted the wound healing activity significantly, when compared to the control group of animals. Ethanol extract possess better wound healing property than the aqueous extract.
%K Ougeinia oojeinensis
%K wound healing activity
%K neomycin cream
%K epithelialization
%U http://jgpt.co.in/jgpt/index.php/jgptjournal/article/view/92