%0 Journal Article
%T Laparoscopic repair for perforated peptic ulcers with U-CLIP£¿
%A Piero Guglielminotti
%A Roberto Bini
%A Diego Fontana
%A Renzo Leli
%J World Journal of Emergency Surgery
%D 2009
%I BioMed Central
%R 10.1186/1749-7922-4-28
%X We, for first, report our preliminary experience of perforated peptic ulcers' laparoscopic repair using Medtronic U-Clip£¿.From January 2008 to June 2008 we performed laparoscopic repair of perforated peptic ulcers using Medtronic U-Clip£¿ in 10 consecutive patients (6 men and 4 women, from 20 to 65 years-old of age). All the patients presented with iuxtapyloric perforated peptic ulcer, not greater than 10 mm, without signs of sepsis, free from major illnesses. The mini-invasive procedure was performed both by skilled and non-skilled laparoscopic surgeons under experts' surveillance. After it was recognized, perforation was sutured using U-Clip£¿ in a full-thickness manner.We reported no surgical complications in the peri-operative period. The clinical outcome and time needed to perform the intervention didn't change between skilled and non-skilled surgeons. The follow-up at 30 days was good.In our experience, the anastomotic device U-Clip£¿ simplifies laparoscopic repair of perforated peptic ulcer, avoiding the need to perform knots and making the procedure safe and easier.Since the first laparoscopic repair of perforated peptic ulcer by Mouret in 1990 [1], mini-invasive technique has gained large popularity.A research in electronic databases as Pub Med (meta-analysis, randomised control trial) and Cochrane review was conducted to identify the most relevant articles published between 1990 and 2008 regarding laparoscopic repair of perforated peptic ulcers.In a meta analysis, Lau [2] identified that the post operative pain was lower than in open repair, and there was a significant reduction in wound infection, but reoperation rate was higher than open repair. Lau's conclusion was that laparoscopic repair was safe and effective for duodenal and juxtapyloric ulcers in patients without Boey's risk factors [3] (shock, major medical illnesses and longstanding perforation > 24 h).Sanabria et al. [4] in a Cochrane database systematic review state that there were no statisticall
%U http://www.wjes.org/content/4/1/28