%0 Journal Article
%T THE VALIDITY OF THE HAMILTON DEPRESSION RATING SCALE AS A SCREENING AND DIAGNOSTIC INSTRUMENT FOR DEPRESSION IN PATIENTS WITH EPILEPSY
%A Koraliya S. Todorova
%A Valentina S. Velikova
%J Journal of IMAB : Annual Proceeding (Scientific Papers)
%D 2012
%I Peytchinski, Gospodin Iliev
%X Aim: To evaluate the concurrent validity of the Hamilton Depression Rating Scale (HAMD-17) against ICD-10 criteria for depressive disorder and its performance as a screening and diagnostic tool for depression in patients with epilepsy (PWE).Subjects and Methods: One hundred and six PWE underwent clinical psychiatric examination followed by evaluation on HAMD-17. ICD-10 criteria for comorbid depressive disorder were applied. Internal consistency was assessed using Cronbach¡¯s ¦Á. A ¡°receiver operating characteristics¡± (ROC) curve was obtained and the sensitivity, specificity, positive and negative predictive values (PPV, NPV) were calculated for different cut-off points of the HAMD-17.Results: Internal consistency measured by Cronbach¡¯s ¦Á was 0.74. Maximal discrimination between depressed and non depressed was obtained at a cut-off score of 8/9 (sensitivity 0.93, specificity 0.98). High sensitivity and NPV at the same cut-off score (sensitivity 0.93, NPV 1.0) show the screening properties, and high specificity and PPV at cut-offs 9/10, the diagnostic properties of the instrument. The area under the ROC curve (AUC=0.746) indicates the concurrent validity of the HAMD-17 score with the ICD-10 criteria for depressive disorder.Conclusion: The validity of the HAMD-17 against ICD-10 criteria for depressive disorder in PWE in our study is fair. The concurrent administration of diagnostic criteria can ascertain the presence of core symptoms of depression.
%K Psychometric properties
%K HAMD-17
%K Epilepsy
%U http://www.journal-imab-bg.org/issue-2012/book3/JofIMAB2012vol18b3p305-307.pdf