%0 Journal Article
%T Histiocytic/dendritic cell transformation of indolent B-cell neoplasms: Clinical laboratory evidence of lineage conversion in hematolymphoid malignancies
%A Endi Wang
%J Journal of Hematological Malignancies
%D 2012
%I 
%R 10.5430/jhm.v2n1p1
%X It is well known that pluripotent progenitors of normal hematopoietic cells can differentiate into cell lineages that are distinct in morphology, immunophenotype and biological function [1]. The conventional concept holds that once a hematopoietic progenitor is committed to a given lineage, its fate is sealed and irreversible. This phenomenon of lineage commitment has also been universally observed in hematolymphoid neoplasms in the past.
%U http://www.sciedu.ca/journal/index.php/jhm/article/view/822