%0 Journal Article
%T Apocrine gland carcinoma on the right thigh
%A Sergio Renato Pais Costa
%A Alexandre Cruz Henriques
%A Sergio Henrique Horta
%J Einstein (S£¿o Paulo)
%D 2008
%I Instituto Israelita de Ensino e Pesquisa Albert Einstein
%X The authors report a case of cutaneous apocrine ductal carcinomaof the right thigh in a 78-year-old female. Histological examinationrevealed a solid, ductal and glandular tumor with a significantdesmoplastic reaction. The tumor cells showed high-grade cellularatypia, and occasional peritumoral inflammatory infiltration wasalso observed. There were no characteristics of extramammaryPaget¡äs Disease on the overlying skin. The neoplastic cells wereimmunohistochemically positive for S-100 protein, lysozyme andalpha-chymotrypsin, but negative for CEA, EMA, and HMB-45. On thebasis of these findings, the diagnosis of apocrine ductal carcinomawas confirmed. The patient then underwent wide resection of thetumor plus en-bloc radical inguinal lymphadenectomy. The localreconstruction was done by means of a tensor fascia lata flap, noadjuvant treatment was performed. To date, one year on, the patientremains healthy, there being no evidence of tumor recurrence.
%K Carcinoma
%K Carcinoma
%K ductal
%K Apocrine glands/pathology
%K Thigh/pathology
%K Immunohistochemistry
%K Case reports
%U http://apps.einstein.br/revista/arquivos/PDF/283-Einsteinv6n4478-480.pdf