%0 Journal Article %T Emerging roles of extracellular vesicles in the adaptive response of tumour cells to microenvironmental stress %A Paulina Kucharzewska %A Mattias Belting %J Journal of Extracellular Vesicles %D 2013 %I Co-Action Publishing %R 10.3402/jev.v2i0.20304 %X Cells are constantly subjected to various types of endogenous and exogenous stressful stimuli, which can cause serious and even permanent damage. The ability of a cell to sense and adapt to environmental alterations is thus vital to maintain tissue homeostasis during development and adult life. Here, we review some of the major phenotypic characteristics of the hostile tumour microenvironment and the emerging roles of extracellular vesicles in these events. %K extracellular vesicles %K exosomes %K shed microvesicles %K cancer %K tumour microenvironment %K stress response %U http://www.journalofextracellularvesicles.net/index.php/jev/article/view/20304/26320