%0 Journal Article
%T Protein expression changes in breast cancer and their importance
%A Tu£¿ba Semerci Sevimli
%A Murat Sevimli
%A Nurten £¿z£¿elik
%J Dicle Medical Journal
%D 2013
%I Dicle University Medical School
%X Studies about nucleic acids have increased after thepublication of DNA¡¯s three dimensional structure by Watsonand Crick. Nucleic acids are the heritable moleculeswhich contain codes for proteins. Proteins are the mostimportant elements in molecular world because they arethe basic structural and functional components of a livingorganism. Clarifying the celluler events that involve proteinsare important in many areas for example diagnosisand treatment determination of diseases or developmentof new drugs. Proteome that comes from a combinationof the terms protein and genome, is one of the importantfield in these days. The studies in this area have acceleratedand gained a different place especially with afterthe completion of human genome project. In synthesis ofa protein just only genetic information is not enough. Atthe same time the change or changes of a protein afterthe synthesis, the final version and transporting to finallocalization of it also important. Because having defects inmailing cells of breast cancer, the first targets of treatmentmust be proteins. In this way the studies on proteins areimportant to determine prognostic and diagnostic diseasemarkers and also significant for identifying new treatmentstrategies.Key words: Genom, proteom, breast cancer
%K Key words: Genom
%K proteom
%K breast cancer
%U http://www.diclemedj.org/upload/sayi/26/Dicle%20Med%20J-01209.pdf