%0 Journal Article
%T Animal models of listeriosis: a comparative review of the current state of the art and lessons learned
%A Karin Hoelzer
%A R¨¦gis Pouillot
%A Sherri Dennis
%J Veterinary Research
%D 2012
%I BioMed Central
%R 10.1186/1297-9716-43-18
%X 1. Challenges in the study of listeriosis2. Pathophysiology of infections with Listeria monocytogenes3. Listeriosis in humans3.1 Neonatal listeriosis and pregnancy-associated listeriosis3.2 Listeriosis in adult and geriatric patients4. Naturally occuring listeriosis among domestic and non-domestic animals4.1 Listeriosis in ruminants4.2 Listeriosis in monogastric mammals other than non-human primates4.3 Listeriosis in non-human primates4.4 Listeriosis in birds5. Experimental infections before recognition as a foodborne disease5.1 Experimental infections in non-pregnant animals5.2 Experimental infections in pregnant animals6. Mouse models of non-pregnancy-associated listeriosis6.1 Susceptibility differences among mouse strains6.2 Pathogenicity differences among L. monocytogenes strains7. Species-specific interactions between internalines and host cells7.1 Interactions between E-cadherin and InlA7.2 InlB and its three receptors8. Other animal models of non-pregnancy-associated listeriosis8.1. Non-pregnant rat models8.2 Non-pregnant guinea pig models8.3 Non-pregnant rabbits as models of listeriosis8.4 Other non-pregnant rodent models8.5 Non-human primates as models of listeriosis9. Animal models of pregnancy- associated listeriosis9.1 Non-human primates as models of pregnancy-associated listeriosis9.2 Guinea pigs as models of pregnancy-associated listeriosis9.3 Other rodent models of pregnancy-associated listeriosis10. Geriatric models of listeriosis11. Conclusions and lessons learned11.1 Consequences for modeling L. monocytogenes dose-response12. Competing interests13. Authors' contributions14. Acknowledgements15. Endnotes16. ReferencesListeriosis, caused by the gram-positive, facultative intracellular bacterium Listeria monocytogenes, is one of the leading causes of death due to foodborne illness in the industrialized world [1,2]. Listeriosis is a relatively rare but very serious disease, with an estimated hospitalization rate that exceeds 90% and a mortality rate of
%U http://www.veterinaryresearch.org/content/43/1/18