%0 Journal Article
%T Portal-systemic encephalopathy with hypermanganesemia: A case report and review of the literature
%A G¨¹lay Ulusal Okyay
%A Ezgi Co£¿kun Yenig¨¹n
%A Atakan Pirpir
%A Osman Ersoy
%J Dicle Medical Journal
%D 2012
%I Dicle University Medical School
%X Hepatic encephalopathy (HE) is a neuropsychiatric syndromeof patients with chronic liver disease. In addition toammonia levels, increased manganese levels in the brainare also considered as having role in the pathogenesisof HE. On cranial T1-weighted magnetic resonance imaging(MRI), hyperintense and symmetrical globus pallidilinked to the manganese deposition are characteristicfor patients with cirrhosis of the liver. We presented herea case of portal-systemic encephalopathy demonstratedwith typical MR images and increased blood manganeseconcentration.
%K Chronic liver disease
%K manganese
%K T1-weighted hyperintensity
%U http://www.diclemedj.org/upload/sayi/1/DicleMedJ-01106.pdf