%0 Journal Article
%T Determination of Pª²Glu Content in Solid Substance of Tanreqing Injection by RPª²HPLC
%A YANG Qing-lin
%A FU Ya
%J Journal of Chongqing Normal University
%D 2012
%I Chongqing Normal University
%X The content of Pª²Glu in solid substance in Tanreqing injection dose was analyzed. The content of Pª²Glu in solid substance in Tanreqing by RPª²HPLC was determined, and defined the content of Pª²Glu in the solid substance of different batches Tanreqing by comparing with reference of Pª²Glu. In this study the Chromatographic conditions was Sionchrom ODSª²BP(200 mm¡Á4.6 mm,5 ¦Ìm)column, acetonitrile-3.5 mmol/L phosphate buffer(volume ratio 1:99) with pH 3 as mobile phase, the flow rate was 1.0 mL/min, detection wavelength was set at 205 nm, the temperature of column was set at 27 ¡æ. The results showed that the Content of Pª²Glu in different batches were determined in the range of 0.5 %¡«1.2 %, the average value was 0.86%, it was indicated that the content of Pª²Glu in Tanreqing injection dose differs slightly in different batches. The method established in the paper was effective and stable, which is quite important to the quality control of Tanyeqing injection dose.
%K Tanreqing injection dose
%K solid substance
%K Pª²Glu£»RP-HPLC
%U http://journal.cqnu.edu.cn/1205/pdf/120516.pdf