%0 Journal Article %T Migraine life-time prevalence in mental disorders: concurrent comparisons with first-degree relatives and the general population Prevalencia de migra a en trastornos mentales: comparaci車n concurrente con familiares de primer grado y con la poblaci車n general %A Trino Baptista %A Euderruh Uzc芍tegui %A Yinet Arap谷 %A Ana Serrano %J Investigaci車n Cl赤nica %D 2012 %I Scientific Electronic Library Online %X The authors quantified the prevalence of migraine in subjects with mental disorders, first-degree relatives and the adult general population (GP) in M谷rida, Venezuela. After validation, a modified, short version of the Lipton*s diagnostic scale was administered to consecutively admitted in- and out-patients (n = 1059), their first-degree relatives (n = 445) and a probabilistic sample of the GP (n = 516). In the GP, the frequency of migraine (percentage and 95% confidence interval) was 14.9 (11.8-17.9). The migraine frequencies were (percentage and odd ratio probability against the GP: bipolar disorder (15.7%, p = 0.5), schizophrenia (8.3%, p = 0.08), depression and dysthimia (24.4%, p = 0.2), anxiety disorders (10.0%, p = 0.02), personality disorders (11.4%, p = 0.15), all other disorders (15.5%, p = 0.4), relatives of bipolar patients (4.4%, p < 0.001), relatives of schizophrenia patients (3.5%, p = 0.003), and relatives of patients with all other mental disorders (12.8%, p = 0.4). Migraine was more common in women (p < 0.001), and the bipolar patients presented the highest female to male ratio (8:1). A high variability was observed in migraine prevalence among the diagnostic categories, but it was particularly high in subjects with affective disorders, mainly in women, who thus deserve special attention from clinicians. Los autores cuantificaron la prevalencia de migra a en sujetos con trastornos mentales, sus familiares de primer grado y la poblaci車n general (PG) en M谷rida, Venezuela. Se utiliz車 una versi車n abreviada de la escala diagnostica de Lipton. Luego de un estudio de validez, tal escala se administr車 a pacientes ambulatorios u hospitalizados atendidos en forma consecutiva (n = 1.059), a sus familiares de primer grado (n = 445) y a una muestra probabil赤stica de la PG (n = 516). La frecuencia de migra a en la PG (porcentaje e intervalo de confianza de 95%) fue de 14,9 (11,8-17,9). La frecuencia para los diversos trastornos (porcentaje y probabilidad asociada a la raz車n de momios (odds ratio) con respecto a la PG) fue: trastorno bipolar (15,7%, p = 0,5), esquizofrenia (8,3%, p = 0,08), depresi車n y distimia (24,4%, p = 0,2), trastornos de ansiedad (10,0%, p = 0,02), trastornos de personalidad (11,4%, p = 0,15), todos los otros trastornos (15,5%, p = 0,4). En los familiares, la frecuencia fue: trastorno bipolar (4,4%, p < 0,001), esquizofrenia (3,5%, p = 0,003), otros trastornos (12,8%, p = 0,4). El diagn車stico de migra a fue m芍s frecuente en mujeres (p < 0,001), y los sujetos con trastorno bipolar presentaron el mayor 赤ndice mujer:hombre (8:1). S %K cefalea primaria %K comorbilidad %K pacientes psiqui芍tricos %K primary headache %K comorbidity %K psychiatric patients %U http://wwww.scielo.org.ve/scielo.php?script=sci_arttext&pid=S0535-51332012000100005