%0 Journal Article %T Utilidad diagn¨®stica del m¨¦todo de Kramer para la detecci¨®n cl¨ªnica de la hiperbilirrubinemia neonatal Usefullness of the Kramer¡¯s index in the diagnosis of hyperbilirubinemia of the newborn %A Sara M Acosta-Torres %A Marco T Torres-Espina %A Jos¨¦ A Colina-Araujo %A Jos¨¦ A Colina-Chourio %J Investigaci¨®n Cl¨ªnica %D 2012 %I Scientific Electronic Library Online %X El objetivo de la presente investigaci¨®n fue correlacionar los valores s¨¦ricos de bilirrubina con el ¨ªndice de Kramer en un grupo de pacientes con ictericia neonatal de tres diferentes etnias. Representa un estudio prospectivo, aleatorio, observacional descriptivo-anal¨¬tico, longitudinal, comparativo y controlado en 50 reci¨¦n nacidos con ictericia neonatal sin complicaciones. Se dividieron en 3 grupos: A (Control), n = 25 de origen cauc¨¢sico; B, n = 15 de origen ind¨ªgena local Way¨²u y C, n = 10 de origen Afro americano. Al ingreso, a cada neonato se le determinaron las zonas d¨¦rmicas de Kramer y se le tom¨® una muestra de sangre venosa braquial para medir la bilirrubina de ingreso. Los valores al ingreso fueron: bilirrubina s¨¦rica 12,02 ¡À 3,41 mg/dL y el 62,8% estaban en nivel 3 de Kramer. No hubo diferencias entre los grupos ¨¦tnicos estudiados y la correlaci¨®n bilirrubina s¨¦rica-¨ªndice de Kramer fue de r= 0,93 (p < 0,005). Al 3er d¨ªa se empez¨® a notar el descenso de la bilirrubina y de los ¨ªndices de Kramer. El m¨¦todo de Kramer ofrece m¨²ltiples ventajas en la evoluci¨®n del RN ict¨¦rico. No se encontraron diferencias raciales. Se recomienda implementar la aplicaci¨®n de este m¨¦todo de Kramer en todas las unidades de neonatos en los hospitales, preferentemente en aquellas que carezcan de bilirrubin¨®metros transcut¨¢neos The objective of the present study was to correlate seric values of bilirubin with the Kramer¡¯s index in a group of newborns with neonatal jaundice, from three different ethnic groups. This was a prospective, randomized, observational, descriptive-analytical, longitudinal, comparative and controlled study of 50 newborns with neonatal jaundice, without complications. They were divided into three groups: A (Control), n = 25, of Caucasian descent; B, n = 15, of local indigenous descent (Way¨²u) and C, n = 10, of Afro-American descent. Each newborn was screened at the start of the study for their Kramer¡¯s dermic areas and simultaneously, a venous blood sample from the arm was taken for bilirubin quantification. They were compared through a correlation-regression analysis. Values at the beginning of the study were: serum bilirubin 12.02 ¡À 3.41 mg/dL, and 62.8% of neonates were at Kramer¡¯s level 3. There were no differences among the ethnic groups studied and the correlation bilirubin/Kramer¡¯s index was r= 0.93 (p < 0.005). At the third day, both bilirubin and Kramer¡¯s indexes started to decrease. There were no ethnic differences. In conclusion, the Kramer¡¯s method offers multiple advantages to evaluate a jaundiced newborn; it is a safe, non-invasiv %K ictericia %K ictericia neonatal %K bilirrubina %K ¨ªndice de Kramer %K neonatal jaundice %K bilirrubin %K Kramer¡¯s Index %U http://wwww.scielo.org.ve/scielo.php?script=sci_arttext&pid=S0535-51332012000200004