%0 Journal Article
%T Research progress in methods for noninvasive diagnosis of nonalcoholic fatty liver disease
%A BAI Yang
%J Journal of Clinical Hepatology
%D 2013
%I Journal of Clinical Hepatology
%X Liver biopsy (LB) is considered the gold standard for assessing the pathological damage of the liver in nonalcoholic fatty liver disease (NAFLD), but this technique is not widely applied in clinical diagnosis because it is invasive. Rapid progress has been made in the research on the methods for noninvasive diagnosis of nonalcoholic steatohepatitis (NASH) and advanced fibrosis in recent years. Some noninvasive methods with relatively high diagnostic values from the aspects of clinical and biochemical indices, biomarkers, and imaging techniques were reviewed. Currently, it is thought that the noninvasive diagnostic methods for NAFLD still cannot be used as a substitute for LB, but a combination of serum cytokeratin 18 fragments, NAFLD fibrosis score, and FibroScan can make for primary diagnosis of NASH with or without advanced fibrosis, so as to decide the use of LB.
%K fatty liver
%K liver cirrhosis
%K diagnostic techniques
%K digestive system
%U http://www.lcgdbzz.org/qk_content.asp?id=5444&ClassID=829587