%0 Journal Article %T Prolonged Action Potential and After depolarizations Are Not due to Changes in Potassium Currents in NOS3 Knockout Ventricular Myocytes %A Honglan Wang %A Ingrid M. Bonilla %A Xin Huang %A Quanhua He %A Mark J. Kohr %A Cynthia A. Carnes %A Mark T. Ziolo %J Journal of Signal Transduction %D 2012 %I Hindawi Publishing Corporation %R 10.1155/2012/645721 %X Ventricular myocytes deficient in endothelial nitric oxide synthase (NOS3−/−) exhibit prolonged action potential (AP) duration and enhanced spontaneous activity (early and delayed afterdepolarizations) during β-adrenergic (β-AR) stimulation. Studies have shown that nitric oxide is able to regulate various K %U http://www.hindawi.com/journals/jst/2012/645721/