%0 Journal Article
%T Protocol for a systematic review of prognosis after mild traumatic brain injury: an update of the WHO Collaborating Centre Task Force findings
%A Carol Cancelliere
%A J David Cassidy
%A Pierre C£¿t¨¦
%A Cesar A Hincapi¨¦
%A Jan Hartvigsen
%A Linda J Carroll
%A Connie Marras
%A Eleanor Boyle
%A Vicki Kristman
%A Ryan Hung
%A Britt-Marie St£¿lnacke
%A Peter Rumney
%A Victor Coronado
%A Lena W Holm
%A J£¿rgen Borg
%A Catharina Nygren-de Boussard
%A Jean-Luc af Geijerstam
%A Michelle Keightley
%J Systematic Reviews
%D 2012
%I BioMed Central
%R 10.1186/2046-4053-1-17
%X The databases MEDLINE, PsychINFO, Embase, CINAHL and SPORTDiscus were systematically searched (2001 to date). The search terms included 'traumatic brain injury', 'craniocerebral trauma', 'prognosis', and 'recovery of function'. Reference lists of eligible papers were also searched. Studies were screened according to pre-defined inclusion and exclusion criteria. Inclusion criteria included original, published peer-reviewed research reports in English, French, Swedish, Norwegian, Danish and Spanish, and human participants of all ages with an accepted definition of MTBI. Exclusion criteria included publication types other than systematic reviews, meta-analyses, randomized controlled trials, cohort studies, and case-control studies; as well as cadaveric, biomechanical, and laboratory studies. All eligible papers were critically appraised using a modification of the Scottish Intercollegiate Guidelines Network (SIGN) criteria. Two reviewers performed independent, in-depth reviews of each eligible study, and a third reviewer was consulted for disagreements. Data from accepted papers were extracted into evidence tables, and the evidence was synthesized according to the modified SIGN criteria.The results of this study form the basis for a better understanding of recovery after MTBI, and will allow development of prediction tools and recommendation of interventions, as well as informing health policy and setting a future research agenda.Traumatic brain injury (TBI) is a leading cause of death and disability [1]. Increasingly, mild (M)TBI (concussion) has been recognized as a public-health concern especially for teenagers and young adults [2] because it can potentially lead to significant disruptions in education and working life [3]. It is estimated that MTBI represents 70% to 90% of all treated cases of TBI, and that the incidence of hospital treatment in adults with MTBI ranges from about 100 to 300 per 100,000 person-years [2]. However, because a large number of MTBI cases
%U http://www.systematicreviewsjournal.com/content/1/1/17