%0 Journal Article
%T Antiviral Activity of Obtained Extracts from Different Parts of Cupressus sempervirens against Herpes Simplex Virus Type 1
%A Seyed Ahmad Emami
%A Zahra Tayarani-Najaran
%A Masoud Sabouri Ghannad
%A Pezhman Khajeh Karamadini
%J Iranian Journal of Basic Medical Sciences
%D 2009
%I Mashhad University of Medical Sciences
%X Objective(s)The aim of this study was to search for new antiviral agents from herbal medicines. Ethanol extracts of C. semipervirens, C. semipervirens var. horizontalis and C. semipervirens cv. Cereiformis were used in experiments to test their influence on herpes viruses (HSV-1). Materials and MethodsHeLa cells monolayers were infected with herpes viruses (HSV-1). Antiviral activity of the plant extracts assessed using Hematoxylin & Eosin method and observed under a light microscope. All tests were compared with a positive control, acyclovir.ResultsResults showed that all three plants have antiviral activity against HSV-1 virus. The most active extract was the obtained extract from C. semipervirens. Among the different parts of this medicinal plant tested, the fruit¡¯s extract appeared to possess the strongest anti- HSV activity.ConclusionIn conclusion, of the extracts tested in this survey all showed significant antiviral potency.
%K Antiviral activity
%K Cupressus sempervirens
%K Cupressusaceae
%K HSV-1
%U http://www.mums.ac.ir/shares/basic_medical/basicmedjou/88/autumn/tayarani_s.pdf