%0 Journal Article
%T Cadmium transport and tolerance in rice: perspectives for reducing grain cadmium accumulation
%A Shimpei Uraguchi
%A Toru Fujiwara
%J Rice
%D 2012
%I BioMed Central
%R 10.1186/1939-8433-5-5
%X Cadmium (Cd) is a toxic heavy metal and is also known as one of the major environmental pollutants. Moderate Cd contamination of arable soils can result in considerable Cd accumulation in edible parts of crops (Arao and Ae 2003; Arao et al. 2003; Wolnik et al. 1983). Such levels of Cd in plants are not toxic to crops but can contribute to substantial Cd dietary intake by humans (Wagner 1993). In the case of "Itai-itai disease", Cd-polluted rice was the major source of Cd intake in the patients (Yamagata and Shigematsu 1970). This is the early case of chronic Cd toxicity in general populations without specific industrial exposure. Even in recent general populations in Japan, the internal Cd level is higher than those of other countries and this is largely because of daily consumption of Japanese rice which contains relatively high Cd (Watanabe et al., 1996; Watanabe et al. 2000; Tsukahara et al. 2003). Cd concentrations of recent Japanese rice have been constantly higher compared to those of other countries (Watanabe et al., 1996; Shimbo et al., 2001), although the values are much lower than the limit established by the Codex Alimentarius Commission of FAO/WHO (0.4 mg/kg). In some areas in China and Thailand, production of highly Cd-polluted rice and renal disfunctions among populations were reported (Nordberg et al., 1997; Jin et al., 2002; Honda et al., 2010). In the United States, increased consumption of rice and other cereals contributes to the recent increase of the dietary Cd intake (Egan et al. 2007). Many reports suggest importance to consider chronic effects of Cd exposure through foods (Jarup and Akesson 2009). In Japanese populations, the average dietary Cd intake (3.0 ¦Ìg Cd/kg body weight/week) exceeds the tolerable weekly intake (2.5 ¦Ìg Cd/kg body weight) set by the European Food Safety Authority (EFSA) and is about 50% of a provisional tolerable monthly intake (25 ¦Ìg Cd/kg body weight/month) established by the Joint Food and Agriculture Organization/Wo
%U http://www.thericejournal.com/content/5/1/5