%0 Journal Article
%T Method development and validation of hydrochlorothiazide in tablet dosage form by UV spectroscopy
%A Alagar Raja M
%A Selvakumar D
%J International Journal of Research in Pharmaceutical Sciences
%D 2010
%I 
%X A simple, reproducible and efficient spectroscopic method development and validation of hydrochlorothiazide in tablet dosage form. The drug was ermined by using methanol as a solvent for this study, which is determined by spectrophotometrically at 224-nm.the percentage recovery study of the drug for the proposed method range from 99-100%w/v indicating no interferences of the tablet excipients, by using methanol as a solvent. Linearity was obtained in the concentration range 10-50 ¦Ìg/ml for the hydrochlorothiazide with correlation coefficient of 0.9916. The result analysis was validated statistically and recovery studies confirmed the accuracy and precision of the proposed method.
%K Hydrochlorothiazide
%K Methanol
%K UV spectrophotometer.
%U http://ijrps.pharmascope.org/index.php?option=com_jdownloads&Itemid=138&task=view.download&catid=4&cid=67