%0 Journal Article %T Culture medium optimization of -amylase producing organism Mocur spp. using the variable size-simplex algorithm %A Hossein Vahidi %A Bijan Shafagi %A Zahra Mirzabeigi %J DARU : Journal of Pharmaceutical Sciences %D 2005 %I BioMed Central %X Effects of different culture conditions on growth and production of amylase by Mucor sp, using the variable size - simplex design, was investigated. The results showed that the optimum condition are pH of 5.5 -7, temperature of 23.8- 25 oC, shaking rate of 126 -155 rpm, starch at the concentration of 5.6 - 8 g/L and arginin at the concentration of 4.3 - 5.7 g/L. %K Mucor spp %K Optimization %K Simplex Algorithm %K Culture medium %U http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/496.pdf&manuscript_id=496