%0 Journal Article %T MULTICOMPONENT SOLVENT FREE SYNTHESIS OF 3, 4-DIHYDROPYRIMIDINE-2-[1H]-ONE AND 3, 4-DIHYDROPYRIMIDINE-2-[1H]-THIONE %A Arun Goyal %A Harvinder Singh Sohal Sanjay Kumar and Rajshree Khare %J Current Trends in Biotechnology and Chemical Research %D 2012 %I M.M.University Mullana, Ambala %X A one pot, multicomponent condensation of an aldehyde, ethylacetoacetate, and urea/thiourea for the synthesis of 3,4-dihydropyrimidine-2-[1H]-thione/one (DHPMs) under solvent free conditions using CuSO .5H O in high 4 2 yields is described. The present methodology offers several advantages such as high yields %U http://ctbcr.com/index.php/biochem/article/view/13