%0 Journal Article
%T IN-VITRO STUDIES SUGGEST PROBABLE MECHANISM OF EUCALYPTUS OIL FOR ANTI-INFLAMMATORY AND ANTI-ARTHRITIC ACTIVITY
%A Habibur Rahman
%A Chinna M Eswaraiah
%A Kamala Vakati
%A Madhavi P
%J International Journal of Phytopharmacy
%D 2012
%I Scholar Science Journals
%R 10.7439/ijpp.v2i3.507
%X The present study aimed to study in-vitro anti-inflammatory and anti-arthritic activity of Eucalyptus globules oil. Anti-inflammatory activity of Eucalyptus globules oil at 100, 250, 500 mcg/ml were studied using human red blood cell membrane (HRBC) stabilization method and anti-arthritic activity of same concentration using bovine serum albumin denaturation(BSA) method. The effect Diclofenec and Aspirin at concentration of 100, 200 mcg/ml were also assessed as standard drug. Results showed significant (53.48%, 63.73% and 70.66% at 100, 250 and 500 mcg/ml of EGO) protection of HRBC and significant inhibition (16.98%, 58.49%, 66.03% at 100, 250 and 500 mcg/ml of EGO) in BSA denaturation and which are comparable to standard drugs diclofenec and aspirin. This result suggests about their potential action as anti-inflammatory and ant-arthritic activity and sets a platform for therapeutic use.
%K human red blood cell membrane (HRBC)
%K bovine serum albumin (BSA)
%K Eucalyptus globules
%K in-vitro
%K anti-inflammatory
%K anti-arthritic.
%U http://ijpp.ssjournals.com/index.php/journal/article/view/22