%0 Journal Article
%T Emerging treatment approaches in acute lymphoblastic and acute myeloid leukemias
%A Thomas X
%J Blood and Lymphatic Cancer: Targets and Therapy
%D 2012
%I 
%X Xavier ThomasHospices Civils de Lyon, Centre Hospitalier Lyon-Sud, Service d'H¨Śmatologie Clinique, Pavillon Marcel B¨Śrard, Bat.1G, Pierre B¨Śnite, FranceAbstract: The choice of treatment approach in acute leukemia depends on well-established prognostic factors. A number of features can predict the outcome of treatment including cytogenetics and an increasing list of molecular features. These are increasingly being used to direct postinduction therapy and support risk-adapted treatments that should achieve optimal results while minimizing nonrelapse mortality. In addition, they are also molecular targets for a new generation of small molecule inhibitors that are in early development and promise to further improve outcomes in the coming decade.Keywords: acute myeloid leukemia, acute lymphoblastic leukemia, treatment, targeted therapy
%U http://www.dovepress.com/emerging-treatment-approaches-in-acute-lymphoblastic-and-acute-myeloid-a9406