%0 Journal Article
%T Recipient screening in IVF: First data from women undergoing anonymous oocyte donation in Dublin
%A Anthony PH Walsh
%A Ahmed B Omar
%A Kevin D Marron
%A David J Walsh
%A Umme Salma
%A E Scott Sills
%J Reproductive Health
%D 2011
%I BioMed Central
%R 10.1186/1742-4755-8-8
%X Data from tests conducted at baseline for all women enrolling as recipients (n = 225) in the anonymous oocyte donor IVF programme at an urban IVF referral centre during a 24-month period were analysed. Patient age at programme entry and clinical pregnancy rate were also tabulated. All recipients had at least one prior negative test for HIV, Hepatitis B/C, chlamydia, gonorrhoea and syphilis performed by her GP or other primary care provider before reproductive endocrinology consultation.Mean (”ĄSD) age for donor egg IVF recipients was 40.7 ”Ą 4.2 yrs. No baseline positive chlamydia, gonorrhoea or syphilis screening results were identified among recipients for anonymous oocyte donation IVF during the assessment interval. Mean pregnancy rate (per embryo transfer) in this group was 50.5%.When tests for HIV, Hepatitis B/C, chlamydia, gonorrhoea and syphilis already have been confirmed to be negative before starting the anonymous donor oocyte IVF sequence, additional (repeat) testing on the recipient contributes no new clinical information that would influence treatment in this setting. Patient safety does not appear to be enhanced by application of Directive 2004/23/EC to recipients of anonymous donor oocyte IVF treatment. Given the absence of evidence to quantify risk, this practice is difficult to justify when applied to this low-risk population.Since 2006, the European Union Tissues and Cells Directive (Directive 2004/23/EC) has exerted an important regulatory impact on the provision of clinical fertility practice in the E.U [1]. This legislation was designed to ensure the safety of donated tissue including bone marrow, corneas, stem cells and heart valves provided through organ/tissue donation. However, IVF clinics in Europe found that they too were under the remit of this directive, since, from a technical and legislative standpoint, couples were regarded as "donating" their own eggs and sperm to each other during fertility procedures. E.U. member states have applied
%U http://www.reproductive-health-journal.com/content/8/1/8