%0 Journal Article
%T Investigation of the Central and Peripheral Analgesic and Anti-inflammatory Activity of Kutajarishta, an Indian Ayurvedic formulation
%A Ashraful Kabir
%J International Journal of Phytopharmacy
%D 2012
%I Scholar Science Journals
%R 10.7439/ijpp.v2i5.746
%X Kutajarishta (KTJ) is an Ayurvedic formulation approved by the ˇ°National formulary of Ayurvedic Medicine 2011ˇ±, of Bangladesh. It is widely available in the Bangladeshi market as an effective preparation to treat lumbago, sciatia and arthritic pain of joints. Our present studies make an attempt toward identifying probable anti-nociceptive and anti-inflammatory mechanisms of KTJ. KTJ, at three doses, (10mL/kg, 20mL/kg, and 40mL/kg) showed no involvement of the CNS in anti-nociceptive activity of KTJ. Carrageenan induced paw edema and acetic acid writhing tests both gave significant results (P ˇÜ 0.05), indicating possible peripheral analgesic and anti-inflammatory action. Formalin induced paw-licking test showed that KTJ had significant effect in suppressing inflammatory pain (PˇÜ0.05) but not neurogenic pain. Hence our study shows anti-inflammatory and peripheral analgesic action for KTJ.
%U http://ijpp.ssjournals.com/index.php/journal/article/view/29