%0 Journal Article
%T Bone Marrow Derived Mesenchymal Stem Cells ¨CA Boon for the Treatment of Complications in Diabetes Mellitus
%A Pratik M. Pawar
%J International Journal of Pharmaceutical and Phytopharmacological Research
%D 2012
%I International Journal of Pharmaceutical and Phytopharmacological Research
%X Mammal Bone marrow is an invaluable source of Mesenchymal stem cells. Bone Marrow derived Mesenchymal Stem Cells (BM-MSCs) are multipotent, self-renewing cells found in almost all postnatal organs / tissues and are used in the treatment of various disease conditions. Diabetes mellitus is a metabolic syndrome characterized by increased levels of blood glucose leading to various complications like Diabetic Foot, Diabetic Neuropathy, Diabetic Retinopathy, Diabetic Cardiomyopathy and Diabetic Nephropathy. BM-MSCs are able to differentiate into many cell types, and to proliferate ex vivo. These attributes makes them a potential therapeutic tool for cell replacement therapy in diabetes and other diseases. The present review discusses the isolation and culturing of BM-MSCs along with their potential as new therapeutic agent in the treatment of Diabetes related complications and its limitations.
%K Bone marrow
%K Mesenchymal stem cells
%K Diabetes Mellitus
%K Diabetic Foot Ulcer
%K Diabetic Poly Neuropathy
%K Diabetic Retinopathy
%U http://www.eijppr.com/jan-2012/9.pdf