%0 Journal Article
%T In-vitro Antioxidant Activity of Eight Traditionally Used Indian Medicinal Plants
%A Sujith S. Nair
%A Molly Mathew
%A Sreena K.
%J International Journal of Pharmaceutical and Phytopharmacological Research
%D 2012
%I International Journal of Pharmaceutical and Phytopharmacological Research
%X In the present study free radical scavenging activities of eight medicinal plants were evaluated. Free radicals are involved in many disorders like neurodegenerative diseases, cancer and AIDS. Antioxidants due to their scavenging activity are useful for the management of those diseases. The antioxidant activity of all the extract by different method was found to be increasing in dose dependent manner. Phylanthus emblica extract and Curcuma longa extract showed best free radical scavenging activity by DPPH (IC50- 148.76 and 198.0 ¦Ìg/ ml respectively), superoxide scavenging (IC50- 162.28 and 249.66 ¦Ìg/ ml respectively) and by hydrogen peroxide scavenging activity method (IC50 -249.42 and 269.42 ¦Ìg/ ml respectively) and were found to be most potent amongst all the extracts. The IC50 values of all the extract was compared with standard IC50 value and found that all the extract was having significant antioxidant activity (P 0.01). This study supports the contention that traditional medicines remain a valuable source in the potential discovery of natural product pharmaceuticals. The significant antioxidant activity showed by all the selected plant extracts provides a scientific validation for the traditional use of these plants.
%K Antioxidant
%K DPPH
%K Superoxide scavenging
%K H2O2 Scavenging
%U http://www.eijppr.com/sept_oct_2012/4.In-vitro%20Antioxidant%20Activity%20of%20Eight%20Traditionally%20Used%20Indian%20Medicinal%20P.pdf