%0 Journal Article
%T In vitro adherence of Candida albicans isolated from patients with chronic periodontitis
%A Adriana Gadotti Machado
%A Edson Yukio Komiyama
%A Silvana Sol¨Ļo Ferreira dos Santos
%A Antonio Olavo Cardoso Jorge
%J Journal of Applied Oral Science
%D 2011
%I University of S?o Paulo
%X Adherence is considered an extremely important virulence factor in yeast. OBJECTIVE: The aim of this study was to analyze the adherence to epithelial cells of C. albicans isolated from patients with chronic periodontitis in comparison to healthy patients. MATERIAL AND METHODS: Candida albicans cells isolated from individuals with chronic periodontitis (n=25) and healthy controls (n=25) were included in this study. Suspensions of C. albicans (10(6) cells/mL) and epithelial cells (10(5) cells/mL) were mixed and incubated at 37oC for 1 h. The number of yeasts adhered to 25 epithelial cells was counted. RESULTS: The number of C. albicans cells adhered to epithelial cells was statistically higher in the chronic periodontitis group than in the control group (Student's t-test, p=0.000). CONCLUSION:The results of the present study suggest a higher Candida adherence of samples isolated from patients with chronic periodontitis.
%K Candida albicans
%K Cell adhesion
%K Periodontitis
%K Virulence factors
%U http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572011000400015