%0 Journal Article
%T Systematic review of antimicrobial resistance among Gram positive cocci in hospitals in Colombia Revisi¨®n sistem¨¢tica de la resistencia antimicrobiana en cocos Gram positivos intrahospitalarios en Colombia
%A Carmelo Jos¨¦ Espinosa
%A Jorge Alberto Cort¨¦s
%A Juan Sebasti¨¢n Castillo
%A Aura Luc¨ªa Leal
%J Biom¨¦dica
%D 2011
%I Instituto Nacional de Salud
%X Introduction. Bacterial resistance is a public health problem worldwide whose proper management requires knowledge of its presence and its behavior in each region and country. Objectives. A survey of the medical literature was conducted to identify levels of resistance to antibiotic markers in Gram positive bacterial isolates from Colombian hospitals. Materials and methods. A systematic review of the literature included articles indexed in MEDLINE and LILACS. A manual search was made of Colombian scientific journals and other infectious disease literature not available electronically. Results. A total of 34 observational studies were located, including a series of consecutive reports initiated in 2001. Most of the reports came from the city of Bogota. The rate of methicillin resistance for Staphylococcus aureus and coagulase-negative staphylococci in non intensive care unit isolates ranged between 35%-50% and 72%-76%, respectively. Resistance in intensive care unit isolates had a range between 35%-71% and 74%-83%, respectively. The rate of vancomycin-resistant Enterococcus faecium averaged less than 20% over the years but with large annual variation . Conclusions. Resistance markers appeared in high frequency among Gram positive isolates identified in hospitals in major Colombian cities. Introducci¨®n. La resistencia bacteriana es un problema de salud p¨²blica a nivel mundial, cuyo adecuado manejo implica el conocimiento de su presencia y comportamiento en cada uno de los pa¨ªses y regiones del mundo. Objetivos. Describir el perfil de resistencia a los distintos antimicrobianos marcadores en microorganismos Gram positivos identificados en hospitales colombianos. Materiales y m¨¦todos. Se realiz¨® una revisi¨®n sistem¨¢tica de la literatura indexada en Medline y Lilacs, adem¨¢s de la b¨²squeda manual de todos los n¨²meros en revistas colombianas reconocidas y afines a la infectolog¨ªa para identificar referencias no disponibles electr¨®nicamente. Resultados. De 34 estudios observacionales, s¨®lo se cuenta con reportes consecutivos en a os a partir del 2001, estos principalmente para Bogot¨¢. La tasa de resistencia a la meticilina de Staphylococcus aureus y estafilococos coagulasa negativos en Bogot¨¢, de aislamientos en servicios diferentes a la unidad de cuidados intensivos, oscilan de 35 % a 50 % y de 72 % a 76 %, respectivamente; en aislamientos de la unidad de cuidados intensivos, la resistencia oscil¨® de 35 % a 71 % y de 74 % a 83 %, respectivamente. La tasa de resistencia a vancomicina para Enterococcus faecium en Bogot¨¢ es menor de 20 % con variaciones muy grand
%K farmacorresistencia microbiana
%K pruebas de sensibilidad microbiana
%K vigilancia sanitaria
%K Staphylococcus
%K Enterococcus
%U http://www.revistabiomedica.org/index.php/biomedica/article/view/333