%0 Journal Article
%T Determination of Lamotrigine in Pharmaceutical Preparations by Adsorptive Stripping Voltammetry Using Screen Printed Electrodes
%A Olga Dom£¿£¿£¿-nguez-Renedo
%A M. Encarnaci£¿£¿£¿3n Burgoa Calvo
%A M. Julia Arcos-Mart£¿£¿£¿-nez
%J Sensors
%D 2008
%I MDPI AG
%X This paper describes a procedure that has been optimized for the determination of lamotrigine by Differential Pulse Adsorptive Stripping Voltammetry (DPAdSV) using carbon screen-printed electrodes (CSPE) and mercury coated carbon screen-printed electrodes. Selection of the experimental parameters was made using experimental design methodology. The detection limit found was 5.0 x 10-6 M and 2.0 x 10-6 M for the non modified and Hg modified CSPE, respectively. In terms of reproducibility, the precision of the above mentioned methods was calculated in %RSD values at 9.83% for CSPE and 2.73% for Hg-CSPE. The Hg-coated CSPEs developed in this work were successfully applied in the determination of lamotrigine in pharmaceutical preparations.
%K lamotrigine
%K screen-printed electrodes
%K differential pulse adsorptive stripping voltammetry.
%U http://www.mdpi.com/1424-8220/8/7/4201/