%0 Journal Article
%T Optimization of Hydrogen Peroxide Detection for a Methyl Mercaptan Biosensor
%A Zhan-Hong Li
%A Houssemeddine Guedri
%A Bruno Viguier
%A Shi-Gang Sun
%A Jean-Louis Marty
%J Sensors
%D 2013
%I MDPI AG
%R 10.3390/s130405028
%X Several kinds of modified carbon screen printed electrodes (CSPEs) for amperometric detection of hydrogen peroxide (H 2O 2) are presented in order to propose a methyl mercaptan (MM) biosensor. Unmodified, carbon nanotubes (CNTs), cobalt phthalocyanine (CoPC), Prussian blue (PB), and Os-wired HRP modified CSPE sensors were fabricated and tested to detect H 2O 2, applying a potential of +0.6 V, +0.6 V, +0.4 V, £¿0.2 V and £¿0.1 V ( versus Ag/AgCl), respectively. The limits of detection of these electrodes for H 2O 2 were 3.1 ¦ÌM, 1.3 ¦ÌM, 71 nM, 1.3 ¦ÌM, 13.7 nM, respectively. The results demonstrated that the Os-wired HRP modified CSPEs gives the lowest limit of detection (LOD) for H 2O 2 at a working potential as low as £¿0.1 V. Os-wired HRP is the optimum choice for establishment of a MM biosensor and gives a detection limit of 0.5 ¦ÌM.
%K methyl mercaptan
%K hydrogen peroxide
%K amperometric sensor
%K screen printed electrode
%U http://www.mdpi.com/1424-8220/13/4/5028