%0 Journal Article
%T Antimicrobial activity of fractions of red propolis from Alagoas, Brazil Atividade antimicrobiana de fra  es da pr車polis vermelha de Alagoas, Brasil
%A Walfrido Bispo Junior
%A Emilia Oliveira Miranda
%A Valter Alvino
%A Brancilene Araujo
%J Semina : Ci那ncias Biol車gicas e da Sa迆de
%D 2012
%I Universidade Estadual de Londrina
%X The red propolis is a new type of propolis founded in Brazil with large biological action. This study evaluated the antimicrobial activity of ethanol extract and fractions of hexane, chloroform and acetanolica of propolis from the apiary of the state of Alagoas. The microbial strains used were: Shigella flexneri, Proteus vulgaris, Staphylococcus, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli and Candida albicans. The ethanolic extract showed activity against Gram-positive strains (100%), Gram-negative (62.5%) and fungi (100%) with efficiency against 76.9% of all the analyzed strains. The hexanic fraction showed efficiency against 76.9% as observed with the ethanolic extract, though the chloroform fraction showed activity against 92.3% of the strains analyzed. Klebsiella pneumoniae was the only resistant species. The ethyl acetate was the fraction that showed the best antimicrobial activity with efficiency against 100% of all strains analized. Excellent results were observed to Candida albicans mainly with ethyl acetate fraction with the value of minimum inhibitory concentration (MIC) similar to those observed to Gram-positives bacteria. We concluded that the partitions of red propolis showed excellent antimicrobial activity mainly against Gram-positive microorganisms and Candida albicans. Furthermore, we observed the ethyl acetate fraction stood out as a promissory biotechnological product. A pr車polis vermelha, como 谷 conhecida popularmente, 谷 uma pr車polis recentemente encontrada no Brasil e tem potente a  o biol車gica. O presente trabalho avaliou a atividade antimicrobiana do extrato etan車lico e das fra  es hexanica, clorof車rmica e acetan車lica da pr車polis proveniente de api芍rio do estado de Alagoas. As linhagens microbianas utilizadas foram: Shigella flexneri, Proteus vulgaris, Staphylococcus, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli e Candida albicans. O extrato etan車lico apresentou atividade antimicrobiana frente a cepas gram-positivas (100%), gram-negativas (62,5%) e f迆ngicas (100%), com efici那ncia em 76,9% em todas as esp谷cies testadas. A fra  o hexanica mostrou efici那ncia em 76,9% das esp谷cies, semelhante ao extrato bruto; j芍 a fra  o clorof車rmica mostrou atividade frente a 92,3% das esp谷cies analisadas, sendo Klebsiella pneumoniae a 迆nica esp谷cie resistente. A fra  o acetan車lica foi a fra  o que apresentou melhor atividade antimicrobiana com efici那ncia em 100% das esp谷cies analisadas. Perante Candida albicans, observamos exc
%K Red propolis
%K Antibacterial activity
%K Antifungal activity
%K Partitions.
%U http://www.uel.br/revistas/uel/index.php/seminabio/article/view/4589