%0 Journal Article %T Diabetes insipidus: main aspects and comparative analysis with diabetes mellitus Diabetes insipidus: principais aspectos e an¨¢lise comparativa com diabetes mellitus %A Danielly Mesquita Figueiredo %A Fl¨¢via L¨²cia Abreu Rabelo %J Semina : Ci¨ºncias Biol¨®gicas e da Sa¨²de %D 2009 %I Universidade Estadual de Londrina %X Diabetes mellitus is a disease characterized by the excess of sugar in the blood and urine. The two most common types of diabetes are insulin-dependent diabetes mellitus and insulin-resistant diabetes mellitus, both presenting glycemic regulation-damage caused by insulin. Nevertheless, there is another type of diabetes that is less known but not less important, the diabetes insipidus, which is characterized by a problem with the synthesis, secretion or action of the ADH (anti-diuretic hormone) that can result in polyuric syndromes with increased excretion of hypotonic urine. Physiologically, variations in the osmotic pressure activate osmoceptors that stimulate the ADH secretion, increasing water reabsorption in the kidney collection tubes. This article intends to revise a wide-ranging study on diabetes insipidus, aiming at a comparative analysis of the incidence, diagnosis, causes, types, treatment and consequences between diabetes insidipus and diabetes mellitus. Diabetes mellitus and insipidus are two different pathologies with a single similarity that is the diabetes itself, that is, the polyuria established. The knowledge of the significant differences between the pathologies studied is important once diabetes insipidus is less known, but can lead to serious complications if not properly treated. O diabetes mellitus ¨¦ uma doen a caracterizada pelo excesso de a ¨²car no sangue e na urina. Os dois tipos mais comuns de diabetes s o diabetes mellitus insulino-dependente e diabetes mellitus insulino ¨C resistente, e que ambos apresentam comprometimento da regula o da glicemia por a o da insulina. No entanto, existe outra forma de diabetes menos conhecida, mas n o menos importante, o diabetes insipidus, que ¨¦ caracterizado por um dist¨²rbio na s¨ªntese, secre o ou a o do ADH (horm nio antidiur¨¦tico), que pode resultar em s¨ªndromes poli¨²ricas com excre o aumentada de urina hipot nica. Fisiologicamente, varia es na press o osm¨®tica ativam osmorreceptores que estimulam a secre o do ADH e esse aumenta a reabsor o de ¨¢gua nos t¨²bulos coletores renais. O presente artigo prop e revisar um estudo abrangente do diabetes insipidus, visando a uma an¨¢lise comparativa da incid¨ºncia, diagn¨®stico, causas, tipos, tratamento e conseq¨¹¨ºncias entre diabetes insipidus e diabetes mellitus. Diabetes mellitus e insipidus s o duas patologias diferentes com a ¨²nica semelhan a que ¨¦ o pr¨®prio diabetes, isto ¨¦, poli¨²ria estabelecida. O conhecimento das significativas diferen as entre as patologias estudadas ¨¦ importante, uma vez que o diabetes insipidus ¨¦ menos conhecido, por¨¦ %K Diabetes %K Insipidus %K Mellitus %K ADH. %U http://www.uel.br/revistas/uel/index.php/seminabio/article/view/4344